Draw the chair conformation of -D(+) -glucose and -D(+) -glucose. Which one is more stable and why?
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Step 1. Draw a basic Haworth projection with the ring oxygen at the top.
Prevalence of Glucose
As you move around the β-glucose ring, you see that all the substituents are equatorial.
This is the most stable arrangement possible.
In α-glucose, only the OH at C-1 is axial.
Every other aldohexose would have more axial substituents and be less stable.
Glucose is the most common hexose because it is the most stable.
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