Chemistry, asked by gksingh9156, 6 months ago

drugs
Trichloro ethanol and sulphonal are the​

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Answered by ishwargosavi329
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Answered by priyanshi4817
1

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It was discovered in 1832 by Justus von Liebig in Gießen when a chlorination (halogenation) reaction was performed on ethanol.[3][4] Its sedative properties were observed by Rudolf Buchheim in 1861, but only described in detail and published by Oscar Liebreich in 1869;[5] subsequently, because of its easy synthesis, its use became widespread.[6] It was widely used for sedation in asylums and in general medical practice, and also became a popular drug of abuse in the late 19th century. One notable recreational user, for instance, was the poet and illustrator Dante Gabriel Rossetti. Chloral hydrate is soluble in both water and ethanol, readily forming concentrated solutions. A solution of chloral hydrate in ethanol called "knockout drops" was used to prepare a Mickey Finn.[7] More reputable uses of chloral hydrate include as a clearing agent for chitin and fibers and as a key ingredient in Hoyer's mounting medium, which is used to prepare permanent or semipermanent microscope slides of small organisms, histological sections, and chromosome squashes. Because of its status as a regulated substance, chloral hydrate can be difficult to obtain. This has led to chloral hydrate being replaced by alternative reagents[8][9] in microscopy procedures

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