Drugs used in child psychiatry introduction,classification,mode of action,indication
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A problem here is that some of the older antipsychotics did not produce much extrapyramidal adverse effects (EPS), if at all, and were, therefore, atypical in action; thioridazine is an example. In contrast, risperidone, ziprasidone, aripiprazole, blonanserin, and many other newer antipsychotics do produce considerable dose-dependent EPS and akathisia. It would be more accurate to say that the risk of tardive dyskinesia, rather than EPS, differentiates the neuroleptics from the atypical antipsychotics.
In this context, clozapine is a very old drug, dating back to 1960 and even earlier, but belongs to the newer/atypical group in characteristics. Furthermore, the more recent nomenclature (e.g., first vs. second generation drugs) tells us nothing about the drugs, themselves. Thus, nomenclature seems to have arisen more through invention (by authors and pharmaceutical companies) for novelty and marketing value than as a consequence of planning and science.