Drugs which increase stability of liver cyp450 enzymes
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If the drug is being studied as a potential inducer of CYP enzymes, the choice of probe or substrate depends on which CYP enzymes are affected by the inducer. Common probe substrates include midazolam, theophylline, repaglinide, warfarin, and omeprazole for CYP3A4, 1A2, 2C8, 2C9 and 2C19, respectively.
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