Question

effect of alcohol on liver_?​

Answer 1

Answer:

$\underline \mathscr \purple{Question \: : - }$

effect of alcohol on liver_?

$\underline \mathscr \purple{Answer \: : - }$

Effect on liver: Absorbed alcohol is carried directly to the liver, where it becomes the preferred fuel. Use of moderate amounts of alcohol does not cause liver damage, provided adequate nutrition is maintained. However, chronic alcoholism causes the following diseases.

• Alcoholic fatty liver. The liver becomes enlarged, yellow, greasy and firm. Hepatocytes (cells of liver) are distended by large fat globules which push the hepatocyte nucleus against the cell membrane. There is increase in the fat synthesis in the liver
• Alcoholic hepatitis. It is characterised by degeneration of hepatocytes. The damaged (degenerated) hepatocytes are surrounded by polymorphonuclear leucocytes. These hepatocytes may be pale and swollen and some contain dense eosinophilic masses called Mallory's hyaline.
• Alcoholic cirrhosis. With continued alcohol intake, there is destruction of hepatocytes and fibroblasts (cells which form fibres) and stimulation of collagen protein formation.
• Cholestasis (Gr. Chole-bile, stasis - a standing still). It is stoppage in the flow of bile. It is characterised by jaundice, abdominal pain and hepatomegaly (enlargement of liver).