Effect of probenecid on tubular excretion of penicillin
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It inhibits the tubular reabsorption of urate, thus increasing the urinary excretion of uric acid and decreasing serum urate levels. ... Probenecid inhibits the tubular secretion of penicillin and usually increases penicillin plasma levels by any route the antibiotic is given.
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It inhibits the tubular reabsorption of urate thus increasing the urinary excretion of uric acid and decreasing serum urate levels probenecid inhibits the tubular secretion in penicillin and usually increase Penicillin plasma levels by any route the antibiotic is given .
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