Effects of low gravity on the size of the lungs
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Gravity causes uneven ventilation in the lung through the deformation of lung tissue (the so-called Slinky effect), and uneven perfusion through a combination of the Slinky effect and the zone model of pulmonary perfusion.
One of the major effects of weightlessness that is more long-term is the loss of muscle and bone mass. In the absence of gravity there is no weight load on the back and leg muscles, so they begin to weaken and shrink.
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