Question

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Give the Williamson synthesis reaction and explain it.
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Answer 1

Answer:

The Williamson ether synthesis is an SN2 reaction in which an alkoxide ion is a nucleophile that displaces a halide ion from an alkyl halide to give an ether. The reaction occurs with inversion of configuration at chiral centers and can be limited by possible competing elimination reactions.

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Answer 2

Answer:

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Reaction of Williamson Synthesis

The Williamson ether synthesis is an organic reaction, forming an ether from an organohalide and a deprotonated alcohol (alkoxide). This reaction was developed by Alexander Williamson in 1850. Typically it involves the reaction of an alkoxide ion with a primary alkyl halide via an SN2 Reaction.

It is used for the preparation of simple as well as mixed ethers. Alkyl halide is heated with alcoholic sodium or potassium alkoxide to form corresponding ethers. Thus, methyl iodide, on heating with alcoholic sodium methoxide forms dimethyl ether.

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