Question

Enlist carcinogenic compounds and explain process of chemical carcinogenesis.

Answer 1

A carcinogen is any substance, radionuclide, or radiation that promotes carcinogenesis, the formation of cancer. This may be due to the ability to damage the genome or to the disruption of cellular metabolicprocesses.

Answer 2

Chemical carcinogens are seen as primary reagents in the etiology of cancer. They may bond covalently or noncovalently to DNA, RNA, and proteins. In the initiation of cancer, carcinogens mutate genes and alter the transcription of the genome. They show no common structures, and many of them are activated by metabolic alteration; alkylation, oxidation, or dealkylation.