Enterochromaffin cell in stomach secrets ______.
Answers
Answer:
histamine
Explanation:
“Enterochromaffin-like (ECL) cells” are a population of cells that are found in the gastric pits of the stomach luminal epithelium and secrete histamine. In response to gastrin released by neighbouring G-cells, secreted histamine from ECL cells acts on parietal cells to stimulate the release of gastric acid.
ECL cells synthesize and secrete histamine in response to stimulation by the hormones gastrin and pituitary adenylyl cyclase-activating peptide. Gastrin itself is secreted by cells in the epithelium of the stomach, but travels to ECL cells via the blood. Together, histamine and gastrin are primary positive regulators of acid secretion from the parietal cell. ECL cells also secrete pancreastatin and probably are the source of one or more other peptide hormones and growth factors. ECL cells are readily identified in histologic sections stained by silver impregnation