Enzyme pepsin works in the pH range 1.5 to 2.5. What would happen to the rate of the reaction controlled by this enzyme, if there is a rise in pH from 2.5 to 8?
The rate doubles
The rate starts to decrease
There will be no effect on rate
The rate first increases then decreases
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Pepsin Pearls
Parietal cells within the stomach lining secrete hydrochloric acid that lowers the pH of the stomach. A low pH (1.5 to 2) activates pepsin. Acetylcholine, gastrin, and histamine stimulate the proton pump in parietal cells to release hydrogen ions and decrease pH.09-May-2021
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