Ethyl iodide to 2- Ethyl propanedioic
Answers
Answer:
PubChem CID
2826993
Structure
Isoquinolinium, 2-ethyl-, iodide_small.png
Isoquinolinium, 2-ethyl-, iodide_3D_Structure.png
Find Similar Structures
Molecular Formula
C11H12IN
Synonyms
2-ethylisoquinolin-2-ium iodide
Isoquinolinium, 2-ethyl-, iodide
N-ethylisoquinolinium iodide
SCHEMBL3633185
SCHEMBL10482528
Diethyl phenylmalonate is an aromatic malonic ester used in the synthesis of moderate to long lasting barbiturates such as phenobarbital.[1]
Unlike other malonic esters that are derived via malonic ester synthesis, diethyl phenylmalonate is typically indirectly derived via a Claisen condensation with diethyl oxalate and ethyl phenylacetate followed by decarbonylation.[2] This indirect method is often used because aryl halides are relatively weaker electrophiles than alkyl halides and thus poorly alkylate diethyl malonate.[3] Methods using Caesium carbonate and copper(I) iodide have been developed to overcome this difficulty however.[4]