evolution of semi solid dosages form
Answers
Answer:
Semisolid pharmaceutical systems comprise a body of
products, which when applied to the skin or accessible
mucous membranes tend to alleviate or treat a pathological
condition or offer protection against a harmful environment.
They have the property to cling to the skin or mucous
membrane for a protracted period of time to exert their
therapeutic effect through protection and occlusion.
The adhesion is due to their plastic rheological behavior
which allows semisolid to retain their shape and cling as
film until acted upon by an outside force.
Semisolid dosage forms usually are intended for localized drug
delivery. In the past few years, however, these forms also have been
explored for the systemic delivery of various drugs.
Semisolids constitute a significant proportion of pharmaceutical dosage
forms.
They can be applied topically to the skin, cornea, rectal tissue, nasal
mucosa, vagina, buccal tissue, urethral membrane, and external ear
lining.
DEFINITION
Semisolid dosage forms are dermatological products of semisolid
consistency which are applied to skin or mucous membrane for
therapeutic or protective action or cosmetic function.
Explanation: