Example of decarboxylation of sodium proanoil
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✍️There are some examples of decarboxylation reactions in which the carbanion intermediate goes on to form a new carbon-carbon bond, rather than becoming protonated as in the example we have seen so far. This reaction in the fatty acid biosynthetic pathway is a decarboxylation followed by a Claisen condensation.
✍️For example, if you heat sodium ethanoate with soda lime, you get methane gas formed: This reaction can be done with certain carboxylic acids themselves. For example, benzene can be made by heating soda lime with solid benzoic acid (benzenecarboxylic acid), C6H5COOH.
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