Question

example of piperazine derivative​

Answer 1

Answer:

Many piperazine derivatives have antipsychotic activity; these compounds mainly act as dopaminergic antagonists, for example, clozapine (10), quetiapine (17) and trifluoperazine (18) 16-19; other piperazine derivatives with similar therapeutic activity and different pharmacodynamic mechanisms . Diethylcarbamazine, a derivative of piperazine, is used to treat some types of filariasis.The piperazine derivatives include 1-benzylpiperazine (BZP), 1,3-trifluoromethylphenylpiperazine (TFMPP), 1-(3-chlorophenyl) piperazine (mCPP) and 1-(4-methoxyphenyl) piperazine (MeOPP); a full summary of their chemical properties is presented in the 'Physical Descriptions' section