Example williamson ether synthesis chemical equation
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Answer:
The Williamson ether synthesis is an organic reaction, forming an ether from an organohalide and a deprotonated alcohol (alkoxide). This reaction was developed by Alexander Williamson in 1850.[2] Typically it involves the reaction of an alkoxide ion with a primary alkyl halide via an SN2 reaction. This reaction is important in the history of organic chemistry because it helped prove the structure of ethers.
Williamson Ether Synthesis
Named after
Alexander William Williamson
Reaction type
Coupling reaction
Identifiers
Organic Chemistry Portal
williamson-synthesis
RSC ontology ID
RXNO:0000090
Ether synthesis by reaction of salicylaldehyde with chloroacetic acid and sodium hydroxide[1]
The general reaction mechanism is as follows:[3]
Williamson ether synthesis mechanism
An example is the reaction of sodium ethoxide with chloroethane to form diethyl ether and sodium chloride:
[Na]+[C2H5O]− + C2H5Cl → C2H5OC2H5 + [Na]+[Cl]