Explain ABO blood group
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Dear Student,
◆ ABO blood group system -
- Carl Landsteiner classified blood groups according to presence/absence of antigens A & B on RBCs.
- Group A have A antigen.
- Group B have B antigen.
- Group AB have both A & B antigen.
- Group O have no antigens.
- Blood group O is called universal donor because it dont have any antigens.
- Blood group AB is called universal acceptor because it doesn't produce any antibodies.
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ABO blood group:
ABO blood group is the process of grouping blood according to the presence or absence of both A and B antigens on the RBC membrane or a and b antibodies in plasma. The theory is presence of "A antigen marks absence" of an antibody in blood and same for B antigen and b antibody.
- The gene of ABO system is present on "chromosome 9" of humans. A and B antigens are oligosaccharides present on RBC membrane.
- Presence of An antigen on RBC and "b antibody in plasma" marks the person A blood grouped.
- Presence of B "antigen on RBC" and an antibody in plasma marks the person B blood grouped.
- The presence of both "A and B antigens" marks the person AB and presence of none of the antigens mark the person O.
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