Question

Explain Amphibolic pathway

Answer 1

Hello Mate,


Amphibolic pathwah are those which contain enzyme that participate in both anabolic and catabolic pathways.It is envolved in the breakdown of acteyl-CoA into oxaloacetate,which is catabolic pathway..


Hope this helps you

Answer 2

★ Amphibolic pathway:-

→ Glucose is the favoured substance for respiration. All carbohydrates are usually first converted into glucose before they are used for respiration

→ Fats breakdown into glycerol & fatty acids. Fatty acids are degraded to acetyl CoA and enter the pathway.k

→ Glycerol is converted to PGAL and enters the pathway.

→ Proteins are degraded by proteases into amino acids. Each amino acid (after deamination) enters the pathway at some stage within the Krebs' cycle or even as pyruvate or acetyl CoA.

→ The respiratory pathway is generally considered as a catabolic pathway. But it involves both anabolism and catabolism (breakdown). So it is better called as an amphibolic pathway.

Example:- Fatty acids breakdown to acetyl CoA before entering the respiratory pathway. But when the organism needs to synthesise fatty acids, acetyl CoA withdraw from the respiratory pathway.

Similarly, during breakdown and synthesis of protein, respiratory intermediates are involved.