Explain blood cells and it's types
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They begin their life as stem cells, and they mature into three main types of cells— RBCs, WBCs, and platelets. In turn, there are three types of WBC—lymphocytes, monocytes, and granulocytes—and three main types of granulocytes (neutrophils, eosinophils, and basophils). See them in action in "Meet the blood cells".
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Blood cells are the cells which are produced during hematopoiesis and found mainly in the blood. Blood is composed of the blood cells which accounts for 45% of the blood tissue by volume, with the remaining 55% of the volume composed of plasma, the liquid portion of the blood.
There are three types of blood cells. They are:
- Red blood cells (Erythrocytes)
- White blood cells (Leukocytes)
- Platelets (Thrombocytes)
Red Blood Cells (Erythrocytes):
- Most abundant cells in the blood
- Account for approximately 40 to 45 percent of the blood.
- Biconcave disc which is round and flat, sort of like a shallow bowl.
- Disk diameter of approximately 6.2-8.2 µm.
- They have a thick rim and a thin sunken center.
- Nucleus Absent.
- Can change shape without breaking.
- Production of RBCs is controlled by erythropoietin.
- RBC contains hemoglobin (33%).
- The iron found in hemoglobin gives the blood its red color.
- RBCs cannot repair themselves.
- Life span of 120 days.
- 4 million new erythrocytes are produced per second in human adults.
- 20–30 trillion red blood cells at any given time.
- Male: 4.3-5.9 million/mm3 and Female: 3.5-5.5 million/mm3
White Blood Cells (Leukocytes)
- Account for only about 1% of the blood.
- 4500-11,000/mm3
- They are the cells that make up the majority of the immune system.
- It is the part of the body that protects itself against foreign substances and various types of infections.
- They are made in the bone marrow from multi-potent cells called hematopoietic stem cells.
- They exist in all parts of the body, including the connective tissue, lymph system, and the bloodstream.
- Leukopenia is a low white blood cell count that can be caused by damage to the bone marrow from things like medications, radiation, or chemotherapy.
- Leukocytosis is a high white blood cell count that can be caused by a number of conditions, including various types of infections, inflammatory disease in the body.
- They are divided into Granulocytes (having visible granules or grains inside the cells) and Agranulocytes (free of visible grains under the microscope).
- There are five main types of WBCs.: Neutrophils (granulocytes), Eosinophils (granulocytes), Basophils (granulocytes), Lymphocytes (non-granulocytes) and Monocytes (non-granulocytes).
platelet:
- Do not reproduce.
- Small fragments of bone marrow cells.
- 150,000–400,000 platelets in each microliter of human blood.
Functions:
- Platelets are the parts of cells that the body uses for clotting.
- Helps to promote other blood clotting mechanisms. Example: Secrete procoagulants (clotting factors) to promote blood clotting.
- They secrete vasoconstrictors which constrict blood vessels, causing vascular spasms in broken blood vessels.
- They secrete chemicals that attract neutrophils and monocytes to sites of inflammation.
- Dissolve blood clots when they are no longer needed.
- Digest and destroy bacteria.
- They secrete growth factors to maintain the linings of blood vessels.
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