explain blood clotting mechanism in human beings for 5 marks
Answers
Answer:
The tissue factor pathway and the contact pathway are the two primary pathways that cause blood coagulation. The tissue factor pathway, the only one of these pathways, is active during normal hemostasis.
Explanation:
Blood clots are created when the process of coagulation, commonly referred to as clotting, causes blood to transform from a liquid to a gel. Hemostasis, or stopping blood loss from a damaged vessel, may follow, and then there will likely be repair.
The first two procedures make up primary hemostasis.
One is vasoconstriction. When the arterial wall is injured, the body's initial reaction is vasoconstriction. Injury causes vessel walls to contract, reducing blood flow to the injured area.
The second is the Platelet plug. At the site of the damage, platelets collect. They form a "plug" by sticking together. Additionally, platelets initiate secondary hemostasis, a process that results in the formation of a fibrin clot.
Secondary hemostasis
Platelets cannot repair the vessel wall damage on their own. At the wounded site, a clot must form. Several chemicals known as coagulation factors are necessary for a clot to form. Roman numerals I through XIII serve as these factors' designations. The "clotting cascade" is the result of these factors interacting with one another. As a result of this chain of events, fibrin, a nonsoluble plasma protein, is created from fibrinogen, a soluble plasma protein. The proteins in fibrin bind together to create a clot.
The intrinsic and extrinsic routes, which are two distinct but interconnected pathways, play a role in the clotting cascade.