explain buffer capacity in pharmaceutical system
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Answer:
Buffer capacity β: buffer efficiency, buffer index or buffer value Is the resistance of a buffer to pH changes upon the addition of a strong acid or base. Definition The ratio of amount added of strong base (or acid) to small change in pH brought about by this addition.
Answer:
Here is your answer
The buffer capacity is defined as the amount of acid or base you can add without changing the pH by more than 1 pH unit.
In pharmaceutical systems: Buffers are widely used in the field of pharmacy as ingredients in most of the pharmaceutical formulations in order to adjust the pH of the product to that required for maximum stability. The ideal pH of a parenteral product is 7.4, which is pH of blood.
OR
Buffer capacity (β) is defined as the moles of an acid or base necessary to change the pH of a solution by 1, divided by the pH change and the volume of buffer in liters; it is a unitless number. A buffer resists changes in pH due to the addition of an acid or base though consumption of the buffer.
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