explain Electrophilic substitutions in amines.
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They are derivatives of ammonia where one or more hydrogen atom is replaced by substituent such as alkyl or aryl group. ... Amines act as nucleophiles due to the presence of lone pair of electrons in the nitrogen atom. They are involved in reactions such as acylation, electrophilic substitution, alkylation etc.
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During electrophilic reaction, the main problem encountered is the high reactivity of aromatic amines. Substitution occurs at ortho and para positions. ... The desired substitution reaction is then carried out followed by the hydrolysis of substituted amides to substituted amines.
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