Explain Forbidden Clones?
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widely accepted one has been the "forbidden clone" concept, which states that when a clone of cells arises that is capable. of recognizing and reacting against self, that clone is elimi- nated (1-3).
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- A hypothetical clone of immunologically competent cells with specificity for some autoantigen that, in accord with the clonal selection theory, has become suppressed in the fetus but may be reactivated in adult life and cause an autoimmune disease.
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