Explain Forbidden Clones?
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Clones refer to producing genetically identical individuals. Forbidden clones refer to clones of those cells which has immunological reactivity with self antigens. Embryonic life is eliminated from these types of clones. Such type of clones is called ‘forbidden clones’.
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A hypothetical clone of immunologically competent cells with specificity for some autoantigen that, in accord with the clonal selection theory, has become suppressed in the fetus but may be reactivated in adult life and cause an autoimmune disease.
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