Explain how DNA, which is six feet long, can be stored in the nucleus of a tiny human cell.
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Explanation:
Packed inside the nucleus of every human cell is nearly 6 feet of DNA, which is divided into 46 individual molecules, one for each chromosome and each about 1.5 inches long. Packing all this material into a microscopic cell nucleus is an extraordinary feat of packaging. For DNA to function, it can't be crammed into the nucleus like a ball of string. Instead, it is combined with proteins and organized into a precise, compact structure, a dense string-like fiber called chromatin.
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DNA hat is six feet long, can be stored in the nucleus of a tiny human cell due to compact packaging.
- Around 2.2m of DNA is extensively packed in the form of 46 chromosomes within the nucleus of a human cell.
- DNA is negatively charged. It is compactly packed around positively charged basic proteins called histone proteins.
- DNA strands are wrapped around a structure called the histone octamer. The structure thus formed is called a nucleosome.
- This structure is unique to the eukaryotic nucleus like the human cell.
- The nucleosomes are further packed to form chromatin fibers that condense to form chromosomes.
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