Question

Explain how Eli Lily an American company

produced insulin by recombinant DNA

technology.​

Answer 1

Answer:

Hope my answer is helpful to you!

Explanation:

In 1983, Eli Lilly, an American company, first prepared two DNA sequences corresponding to A and В chains of human insulin and introduced them in plasmids of E. coli to produce insulin chains. Chains A and В were produced separately, extracted and combined by creating disulfide bonds to form human insulin (humulin).

Answer 2

$\huge\bold\red{Answer}$

ᴛʜᴇ ᴍᴀɴᴀɢᴇᴍᴇɴᴛ ᴏғ ᴀᴅᴜʟᴛ-ᴏɴsᴇᴛ ᴅɪᴀʙᴇᴛᴇs ɪs ᴘᴏssɪʙʟᴇ ʙʏ ᴛᴀᴋɪɴɢ ɪɴsᴜʟɪɴ ᴀᴛ ʀᴇɢᴜʟᴀʀ ᴛɪᴍᴇ ɪɴᴛᴇʀᴠᴀʟs.

ɴᴏᴡ, ɪᴛ ɪs ᴘᴏssɪʙʟᴇ ᴛᴏ ᴘʀᴏᴅᴜᴄᴇ ʜᴜᴍᴀɴ ɪɴsᴜʟɪɴ ᴜsɪɴɢ ʙᴀᴄᴛᴇʀɪᴀ.

ɪɴsᴜʟɪɴ ғʀᴏᴍ ᴛʜᴇ ᴘᴀɴᴄʀᴇᴀs ᴏғ ᴀɴɪᴍᴀʟs (ᴄᴀᴛᴛʟᴇ ᴀɴᴅ ᴘɪɢs) ᴄᴀᴜsᴇs ᴀʟʟᴇʀɢʏ ᴏʀ ᴏᴛʜᴇʀ ᴛʏᴘᴇs ᴏғ ʀᴇᴀᴄᴛɪᴏɴs ᴛᴏ ᴛʜᴇ ғᴏʀᴇɪɢɴ ᴘʀᴏᴛᴇɪɴ.ɪɴsᴜʟɪɴ ᴄᴏɴsɪsᴛs ᴏғ ᴛᴡᴏ sʜᴏʀᴛ ᴘᴏʟʏᴘᴇᴘᴛɪᴅᴇ ᴄʜᴀɪɴs (ᴄʜᴀɪɴ ᴀ ᴀɴᴅ ᴄʜᴀɪɴ ʙ) ᴛʜᴀᴛ ᴀʀᴇ ʟɪɴᴋᴇᴅ ᴛᴏɢᴇᴛʜᴇʀ ʙʏ ᴅɪsᴜʟᴘʜɪᴅᴇ ʙʀɪᴅɢᴇs.ɪɴ ᴍᴀᴍᴍᴀʟs, ɪɴsᴜʟɪɴ ɪs sʏɴᴛʜᴇsɪᴢᴇᴅ ᴀs ᴀ ᴘʀᴏ-ʜᴏʀᴍᴏɴᴇ. ᴛʜᴇ ᴘʀᴏ-ʜᴏʀᴍᴏɴᴇ ɴᴇᴇᴅs ᴘʀᴏᴄᴇssɪɴɢ ʙᴇғᴏʀᴇ ɪᴛ ʙᴇᴄᴏᴍᴇs ᴀ ғᴜʟʟʏ ᴍᴀᴛᴜʀᴇ ᴀɴᴅ ғᴜɴᴄᴛɪᴏɴᴀʟ ʜᴏʀᴍᴏɴᴇ.ᴛʜᴇ ᴘʀᴏ-ʜᴏʀᴍᴏɴᴇ ᴄᴏɴᴛᴀɪɴs ᴀɴ ᴇxᴛʀᴀ sᴛʀᴇᴛᴄʜ ᴄᴀʟʟᴇᴅ ᴛʜᴇ ᴄ ᴘᴇᴘᴛɪᴅᴇ.

ᴛʜɪs ɪs ʀᴇᴍᴏᴠᴇᴅ ᴅᴜʀɪɴɢ ᴍᴀᴛᴜʀᴀᴛɪᴏɴ ɪɴᴛᴏ ɪɴsᴜʟɪɴ. ɪɴ 1983, ᴇʟɪ ʟɪʟʏ ᴀɴᴅ ᴀᴍᴇʀɪᴄᴀɴ ᴄᴏᴍᴘᴀɴʏ ᴘʀᴇᴘᴀʀᴇᴅ ᴛᴡᴏ ᴅɴᴀ sᴇǫᴜᴇɴᴄᴇs ᴄᴏʀʀᴇsᴘᴏɴᴅɪɴɢ ᴛᴏ ᴀ ᴀɴᴅ ʙ ᴄʜᴀɪɴs ᴏғ ʜᴜᴍᴀɴ ɪɴsᴜʟɪɴ, ɪɴᴛʀᴏᴅᴜᴄᴇᴅ ᴛʜᴇᴍ ɪɴ ᴘʟᴀsᴍɪᴅs ᴏғ ᴇ. ᴄᴏʟɪ ᴛᴏ ᴘʀᴏᴅᴜᴄᴇ ɪɴsᴜʟɪɴ ᴄʜᴀɪɴs. ᴄʜᴀɪɴs ᴀ ᴀɴᴅ ʙ ᴡᴇʀᴇ ᴘʀᴏᴅᴜᴄᴇᴅ sᴇᴘᴀʀᴀᴛᴇʟʏ, ᴇxᴛʀᴀᴄᴛᴇᴅ ᴀɴᴅ ᴄᴏᴍʙɪɴᴇᴅ ʙʏ ᴄʀᴇᴀᴛɪɴɢ ᴅɪsᴜʟғɪᴅᴇ ʙᴏɴᴅs ᴛᴏ ғᴏʀᴍ ʜᴜᴍᴀɴ ɪɴsᴜʟɪɴ.