Question

Explain in detail about Krebs cycle.

Answer 1

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$\Huge{\red{\underline{\textsf{Explaination}}}}$

$\purple\bigstar$Krebs cycle :-

$\orange\star$ Pyruvic acid produce during Glycolysis undergoes aerobic oxidation in the mitochondrial matrix through TCA cycle.

$\orange\star$ It is common oxidative pathway for carbohydrate, fat, proteins.

$\orange\star$ Intermediate compounds are used in synthesis of glutamate and asprated.

$\orange\star$ First pyruvic acid enter into mitochondria then it is decarboxylated and remaining 2 carbon fragment combines with Co enzyme A to form acetyl Co - A.

$\orange\star$ It is oxidative decarboxylation process which produces $\sf H_^{+}$ ions, electrons and carbon dioxide.

$\orange\star$ $\sf \beta$ oxidation of fatty acid produces acetyl co - A.

$\orange\star$ Acetyl Co-A condensed with oxyaloacetate to form citric acid.

$\orange\star$ The mitochondrial enzyme envoled to oxidise citric acid and releases carbon dioxide and oxyaloacetate regenerated again to complete cycle.

$\orange\star$ In this cycle 4 steps of oxidation is carried by dehydrogenase using an enzyme $\sf NAD^{+}$ and $\sf FAD^{+}$

$\orange\star$ Co enzymes are produced to$\sf NAD^{+}H^{+}$ and $\sf FADH_2$. This transfer their electron to the mitochondrial respiratory chain.

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