explain koch's postulate with reference to mycobacterium tuberculosis
Answers
For diseases like tuberculosis, these postulates have been quite successful. Koch was able to visualize Mycobacterium tuberculosis in diseased to reproduce the disease in animals upon inoculation from pure culture. Animals and people without disease were found not to have M. tuberculosis in tissues.
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Explanation:
The microorganism must be found in abundance in all organisms suffering from the disease, but should not be found in healthy organisms.
The microorganism must be isolated from a diseased organism and grown in pure culture.
The cultured microorganism should cause disease when introduced into a healthy organism.
The microorganism must be reisolated from the inoculated, diseased experimental host and identified as being identical to the original specific causative agent.