Question

Explain Mac Leod, McCarty and Avery`s work that followed Griffith`s experiment. State the conclusion they arrived at.

Answer 1

Answer:

Prior to the work of Oswald Avery, Colin Macleod and Maclyn Mccarty, the genetic material was thought to be a protein.

* They purified biochemicals (proteins, DNA, RNA etc) from the heat killed S-cells to see which could transform live R cells into S cells.

* They discovered that only DNA alone from S bacteria caused R bacteria to transform.

* They discovered that proteases and RNAses did not affect the transformation and hence concluded that transforming principle was not a protein or RNA.

* Digestion with DNase did not affect transformation and thus concluded that DNA was the genetic material.

Answer 2

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Here is your answer❣️

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a) In 1928, Fredrick Griffith, in a series of experiments with Streptococcus pneumoniae (bacterium responsible for pneumonia), witnessed a miraculous ...