Explain nucleic acid hybridization.
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Nucleic acid hybridization is a method in which single-stranded nucleic acids are permitted to associate so that edifices called cross breeds are shaped by particles with comparable, correlative groupings.
Through nucleic corrosive hybridization, the level of arrangement personality between nucleic acids can be resolved and explicit successions identified in them. The hybridization can be done in arrangement or with one segment immobilized on a gel or, most normally, on nitrocellulose paper .
Through nucleic corrosive hybridization, the level of arrangement personality between nucleic acids can be resolved and explicit successions identified in them. The hybridization can be done in arrangement or with one segment immobilized on a gel or, most normally, on nitrocellulose paper .
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---> This is a method in which DNA and RNA interact with each other making new complexes called hybrids.
---> Hybrids are made between complementary sequences.
---> This method is useful in recognizing certain sequences.
---> Hybridization can occur between DNA-DNA, RNA-RNA and DNA-RNA.
---> Usually there are three ways in which nucleic acid hybridization occurs i.e. :
• In a solution
• On a gel
• On nitrocellulose paper
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