Question

Explain oxygen dissociation curve.

Answer 1

Answer:

The oxygen–hemoglobin dissociation curve, also called the oxyhemoglobin dissociation curve or oxygen dissociation curve, is a curve that plots the proportion of hemoglobin in its saturated form on the vertical axis against the prevailing oxygen tension on the horizontal axis.

Answer 2

Oxygen dissociation curve:

Binding of O2 with Hb is related to partial pressure of O2.

A sigmoid curve is obtained when percentage saturation of Hb with O2 is plotted against pO2. This curve is called Oxygen Dissociation Curve.

Factors affecting dissociation curve are pCO2, H+ concentration and temperature.

In the alveoli, high pO2, low pCO2, lesser H+ concentration and lower temperature are favourable for the formation of oxyhemoglobin.

In tissues, low pO2, high pCO2, high H+ concentration and higher temperature are favorable for dissociation of O2 from oxyhemoglobin.

Thus, O2 gets bound to Hb in the lung surface and gets dissociated at the tissues.

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