explain PDH complex or explain how acetyle COA
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Pyruvate dehydrogenase complex (PDC) is a complex of three enzymes that converts pyruvate into acetyl-CoA by a process called pyruvate decarboxylation. ... Pyruvate decarboxylation is also known as the "pyruvate dehydrogenase reaction" because it also involves the oxidation of pyruvate.
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PDH catalyzes the oxidative decarboxylation of pyruvate to produce acetyl coenzyme A (acetyl-CoA), NADH and CO2. PDH facilitates the use of carbohydrate to meet energy demands: when carbohydrate stores are depleted in mammals, PDH activity is downregulated to limit the use of glucose by oxidative phosphorylation
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