Question

Explain Pleotropism with suitable examples.​

Answer 1

Explanation:

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Pleiotropism is a central term in developmental genetics. In pleiotropism, a single gene affects a number of phenotypic traits in the same organism. These pleiotropic effects often seem to be unrelated to each other.

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An example of pleiotropy is phenylketonuria, an inherited disorder that affects the level of phenylalanine in the human body. Phenylalanine is an amino acid that can be obtained from food. Phenylketonuria causes this amino acid to increase in amount in the body, which can be very dangerous.

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Though pleiotropic effects are defined as a single gene affecting multiple systems or determining more than one phenotype, lately statin pleiotropy is referred as statins exerting multiple pharmacological activities.

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Answer 2

Answer:

Pleiotropy (from Greek πλείων pleion, "more", and τρόπος tropos, "way") occurs when one gene influences two or more seemingly unrelated phenotypic traits. An example of pleiotropy is phenylketonuria, an inherited disorder that affects the level of phenylalanine in the human body.