Question

Explain Rate of reaction of acetaldehyde with Aniline increases with increase in acidity but beyond certain limit it decreases with further increase of acidity

Answer 1

Kinetics studies with physically diverse aldehydes and ketones in aqueous buffer at pH 7.4 reveal that carbonyl compounds with neighboring acid/base groups form hydrazones at accelerated rates. Similarly, tests of a hydrazine with a neighboring carboxylic acid group show that it also reacts at an accelerated rate...