Question

Explain respiratory balance sheet 3m

Answer 1

The Respiratory Balance Sheet. The respiratory balance sheet gives theoretical value about net gain of ATP for every glucose molecule oxidized. The calculations for respiratory balance sheet are based on some assumptions which are as follows: ... Glucose is the only substrate undergoing respiration.

Answer 2

★ The respiratory balance sheet:-

→ The net gain of ATP from each glucose molecule can be calculated based on the following assumptions:-

• All steps in Glycolysis, TCA cycle and ETS pathway occur in a sequential and orderly manner.

• The NADH synthesised in glycolysis is transferred into mitochondria and undergoes oxidative phosphorylation.

• None of the intermediates in the pathway are utilised to synthesise any other compound.

• Only glucose is being respired - no other alternative substrates are entering in the pathway at any of the intermediary stages.

→ Such assumptions are not valid because,

o All pathways work simultaneously and do not take place one after another.

o Substrates enter the pathways and are withdrawn from it as and when necessary.

o ATP is utilized as and when needed.

o Enzymatic rates are controlled by multiple l means.

→ Such calculations are useful to appreciate the efficiency of the living system in extraction and storing energy.