Explain the aggregation of cell?
How can a cell be aggregated manually by humans?
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Explanation:
A high cell density is a crucial factor in inducing NKX6.1+ pancreatic bud cells.
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Aggregation cultures efficiently induce NKX6.1+ cells in multiple hiPSC lines.
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The generated cells can differentiate into functional endocrine cells in vivo.
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We propose that pancreatic bud formation is regulated by morphological factors.
Cell aggregation may be prevented by the repulsive effects of the negatively charged sialic acids, as was observed for example when studying the adhesion of cultured cells to their substratum [910], These cells adhered better to a layer of desialylated gangliosides than to the native, negatively charged, species, or ...Explain
Term:cell aggregationDefinition:The clustering together and adhesion of initially separate cells to form an aggregate. Examples include the clustering of unicellular organisms or blood cells in suspension and the condensation of mesenchymal cells during cartilage formation.
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