EXPLAIN THE CHEMICAL NATURE OF-
i) COVAXIN
ii) COVISHIELD
Also mention which one provides more protection against COVID-19 virus and why?
NOTE- • Explain the answers in details. Don't write in short. • Please don't post irrelevant answers or else I will report it
Answers
Explanation:
Covaxin has been developed by Hyderabad-based Bharat Biotech International Ltd in association with the Indian Council of Medical Research (ICMR) and the National Institute of Virology (NIV).
Covishield has been developed by the Oxford-AstraZeneca and is being manufactured by the Serum Institute of India (SII).
Type of Vaccine
Covaxin is an inactivated vaccine, which has been prepared on a tried and tested platform of dead viruses.
This vaccine is developed with Whole-Virion Inactivated Vero Cell-derived technology. They contain inactivated viruses, which can not infect a person but still can teach the immune system to prepare a defence mechanism against the active virus.
These conventional vaccines have been in use for decades now. There are vaccines for some other diseases as well which are made using the same technology. These diseases are –
Seasonal influenza
Rabies
Polio
Pertussis, and
Japanese encephalitis
Covishield has been prepared using the viral vector platform which is a totally different technology.
A chimpanzee adenovirus – ChAdOx1 – has been modified to enable it to carry the COVID-19 spike protein into the cells of humans. Well, this cold virus is basically incapable of infecting the receiver but can very well teach the immune system to prepare a mechanism against such viruses.
The exact technology was used to prepare vaccines for viruses like Ebola.
Doses
There is no difference between the two vaccines in terms of dosage. Both of them follow a two-dose regimen, administered 28 days apart.