Question

Explain the concept of isoenzymes with suitable example

Answer 1

Isozymes (also known as isoenzymes or more generally as multiple forms of enzymes) are enzymes that differ in amino acid sequence but catalyze the same chemical reaction. These enzymes usually display different kinetic parameters (e.g. different KM values), or different regulatory properties.

An example of an enzyme with different isozymes is lactate dehydrogenase (LDH). This enzyme is used to catalyze the synthesis of glucose in anaerobic metabolism of glucose. ... Both isozymes have two polypeptide chains, and each isozyme share 75% of the amino acid sequence for the chains.

Answer 2

Answer :-

In general terms, "Isoenzymes" can simply be defined as the enzymes having similar properties but different molecular weights.

Extra Information :-

• The enzymes which posses slightly different molecular structures but perform identical activities are also known as "Isoenzymes".

• Some enzymes have several molecular forms i.e. 16 for α-amylase (alpha-amylase) and 5 for Lactate Dehydrogenase (L.D.H.).

• "Lactate Dehydrogenase" (L.D.H.) is the isoenzyme which plays an important role in the catalytical conversion of Pyruvic acid into Lactic acid.