Question

Explain the effect of deletion of the gene in an individual. How does gene therapy help in this case?

Answer 1

Explanation:

Phenotypic effects of deletions depend on the size and location of deleted sequences on the genome. For instance, deletions that span a centromere result in. . an acentric chromosome that will most likely be lost during cell division. As with duplications, deletions can affect gene dosage and thus the resulting phenotype.