Question

Explain the following with an example
Williamson ether Synthesis
Unsymmetrical ether​

Answer 1

Explanation:

Williamson ether synthesis:

Williamson ether synthesis is a laboratory method to prepare symmetrical and unsymmetrical ethers by allowing alkyl halides to react with sodium alkoxides.

This reaction involves SN2 attack of the alkoxide ion on the alkyl halide. Better results are obtained in case of primary alkyl halides.

If the alkyl halide is secondary or tertiary, then elimination competes over substitution.

Unsymmetrical ether:

An unsymmetrical ether is an ether where two groups on the two sides of an oxygen atom differ (i.e., have an unequal number of carbon atoms). For example: ethyl methyl ether (CH3-O-CH2CH3).

Answer 2

Answer:

1 Williamson Ether Reactions involve an lakeside that reacts with a primary halo alkane or a sulfonate ester. Lakesides consist of the conjugate base of an alcohol and are comprised of an R group bonded to an oxygen atom. They are often written as RO–, where R is the organic substituent.

Williamson ether diagrams.bmp

Sn2 reactions are characterized by the inversion of stereochemistry at the site of the leaving group. Williamson Ether synthesis is not an exception to this rule and the reaction is set in motion by the backside attack of the nucleophile. This requires that the nucleophile and the electrophile are in anti-configuration.

Explanation: