Explain the Kerb's cycle with reaction?
Answers
Answer:
The reactions which help in converting pyruvic acid to carbon dioxide and water in mitochondria is called Krebs cycle. It is also known as citric acid or tricarboxylic acid cycle (TCA cycle). ... This reaction is catalyzed by an isocitric dehydrogenase. During this reaction, one NADH2 is formed.
Answer:
Kreb's cycle is a cyclic process that occurs in the mitochondrial matrix, in the presence of oxygen.
Step 1: The cycle starts with the condensation of an acetyl group with oxaloacetic acid and water to form citric acid, with a release of CoA molecule. The enzyme involved in this conversion is citrate synthase.
Step 2: Citrate then isomerises to form isocitrate.
Step 3: The synthesis of citrate is followed by two successive steps of decarboxylation — first, the formation of a-ketoglutaric acid, and then, that of succinyl-CoA.
Step 4: This succinyl-CoA gets oxidised to form malic acid, which in turn gets converted into oxaloacetic acid, thereby allowing the cycle to continue.
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