Question

explain the mechanism of intercellular recognition and cell aggregation?

Answer 1

To form an anchoring junction, cells must first adhere. A bulky cytoskeletal apparatus must then be assembled around the molecules that directly mediate the adhesion. The result is a well-defined structure—a desmosome, a hemidesmosome, a focal adhesion, or an adherens junction—that is easily identified in the electron microscope. Indeed, electron microscopy provided the basis for the original classification of cell junctions. In the early stages of cell junction development, however, before the cytoskeletal apparatus has assembled, cells often adhere to one another without clearly displaying these characteristic structures; in the electron microscope, one may simply see two plasma membranes separated by a small gap of a definite width. Functional tests show, nevertheless, that the two cells are stuck to each other, and biochemical analysis can reveal the molecules responsible for the adhesion.

Answer 2

Cell aggregation is defined as the accumulation or group making/bonding of cells at the time of need. For example, cluster formation of platelets at the site of an injury. A special type of platelets joins together and protects the wound for further infection.

Cell recognition is defined as the ability of cells to recognize one another and adhere with each other. Inter-cellular cell recognition is important for their survival and recognition. This interaction can be provided through hormones, chemicals or other kinds of secretions between the cells.