Explain the mechanism of SN2 reaction.
Answers
Answer:
The rate-determining step of this reaction depends on the interaction between the two species, namely the nucleophile and the organic compound.
SN2 reaction mechanism requires the attack of nucleophile from the back side of the carbon atom. So the product assumes a stereochemical position opposite to the leaving group originally occupied. This is called inversion of configuration. The SN2 reaction is a good example of stereospecific reaction, one in which different stereoisomers react to give different stereoisomers of the product. Also, SN2 reaction is the most common example of Walden inversion where an asymmetric carbon atom undergoes inversion of configuration.
Explanation:
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Answer:
The S
N
2 reaction involves displacement of a leaving group (usually a halide or tosylate), by a nucleophile. It is a one-step reaction.
This reaction works the best with methyl and primary halides because bulky alkyl groups block the backside attack of the nucleophile, but the reaction does work with secondary halides (although it is usually accompanied by elimination), and will not react at all with tertiary halides.
In this reaction the inversion of configuration takes place. Thus here backside attack of nucleophile takes place to avoid hindrance due to the high molecular mass groups.
In this mechanism, the bond breaking between C−X and bond formation between C−Nu takes place simultaneously. During this stage energy of the species increases and this stage is known as 'transition stage'.