Question

explain the mechanisms of necrosis.​

Answer 1

Answer:

The mechanism of calcium-overload-mediated cell necrosis involves the activation of proteases and other factors. ... Activation of some phospholipases during necrosis, especially cytosolic Ca 2+-dependent phospholipase A2, may also play a role in cell death

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Answer 2

Answer:

Necrosis is caused by factors external to the cell or tissue, such as infection, or trauma which result in the unregulated digestion of cell components. ... This initiates in the surrounding tissue an inflammatory response, which attracts leukocytes and nearby phagocytes which eliminate the dead cells by phagocytosis.