Explain the two receptor-analyte interaction types with examples.
Answers
In supramolecular chemistry,[1] host–guest chemistry describes complexes that are composed of two or more molecules or ions that are held together in unique structural relationships by forces other than those of full covalent bonds. Host–guest chemistry encompasses the idea of molecular recognition and interactions through non-covalent bonding. Non-covalent bonding is critical in maintaining the 3D structure of large molecules, such as proteins and is involved in many biological processes in which large molecules bind specifically but transiently to one another.
Explanation:
Measurement of the analyte binding rate at the beginning of sample injection
Lectin-based assays may require using an additional reagent . Thus, the anti- α1-acid glycoprotein (anti-AGP) antibody was utilized for capturing the AGP protein from plasma samples .The fucose-binding lectin Aleuria aurantia (AAL) was then injected over the surface. The AAL response was linearly dependent on the average number of fucose residues per AGP molecule
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