explain transforming principle with griffith experiment
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Griffith's experiment was an experiment done in 1928 by Frederick Griffith. It was one of the first experiments showing that bacteria can get DNA through a process called transformation. Griffith used two strains of Streptococcus pneumoniae. These bacteria infect mice, Griffith's favorite animals.
DNA as Genetic Material Griffith experiment was a turning point towards the discovery of hereditary material. However, it failed to explain the biochemistry of genetic material. Hence, a group of scientists, Oswald Avery, Colin MacLeod and Maclyn McCarty continued the Griffith experiment in search of biochemical nature of the hereditary material.
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Griffith concluded that the type II-R had been "transformed" into the lethal III-S strain by a "transforming principle" that was somehow part of the dead III-S strain bacteria. Today, we know that the "transforming principle" Griffith observed was the DNA of the III-s strain bacteria.
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