explain two examples of feedback inhibition using a
flowsheet diagram?
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Answer:
Feedback Inhibition Definition
Feedback inhibition is a cellular control mechanism in which an enzyme’s activity is inhibited by the enzyme’s end product. This mechanism allows cells to regulate how much of an enzyme’s end product is produced.
Most biochemical processes are complex and multi-step, requiring multiple enzymes to get from the starting substrate to the desired end product.
Typically, feedback inhibition acts on the first enzyme unique to a given pathway. For example, in the case of amino acid production, an amino acid may act as an inhibitor for the first enzyme in the pathway whose purpose is making more of that amino acid.
The graphic below illustrates this process:
Feedback inhibition is usually accomplished through something called an “allosteric site” – a site on an enzyme that changes the shape of an enzyme, and subsequently the behavior of the
good example of this is the production of ATP from glucose. The enzymes that produce ATP from glucose are subject to feedback inhibition by ATP. This saves glucose by preventing its unnecessary breakdown when the cell has plenty of ATP.