explain what is Rh-factor......???????
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Rh-factor
In 1940, Landsteiner and Weiner discovered that apart from antigen A and B, another antigen discovered from Rhesus monkey, may be present on the surface of the RBCs in many people. This antigen was named as Rh-factor or Rhesus factor. The people (almost 85%- 90%) who possess the Rh-factor are called Rh+ and those who do not possess this factor are called Rh-
In 1940, Landsteiner and Weiner discovered that apart from antigen A and B, another antigen discovered from Rhesus monkey, may be present on the surface of the RBCs in many people. This antigen was named as Rh-factor or Rhesus factor. The people (almost 85%- 90%) who possess the Rh-factor are called Rh+ and those who do not possess this factor are called Rh-
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Rh-factor
⇒ Rh-factor is associated with Rh-antigen.
⇒ Rh-factor was discovered by Landsteiner and Veiner in 1940 in rhesus monkey.
⇒ Genes, which control Rh-factor are present on autosomes.
⇒ No natural Rh antibodies are found in blood of man. But if ⁺ blood is mixed with ⁻ blood then antibodies formation starts, i.e. , antibodies against Rh antigen are produce in ⁻ blood.
⇒ Marriage of ⁺ man and ⁻ woman is prohibited because due to this first birth is safe, while second is fatal. This disease is known as erythroblastosis foetalis.
⇒ Now-a-days IgG ( Immunoglobulin preparation ) is given to each ⁻ woman after first birth for prevention.
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