explain why father never passes on a haemophilia gene to his son? even with this condition haemophilia victims are mostly men while women are rarely affected. give reasons
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The haemophilia is a defect that has been found to occur due to a recessive mutation of a gene locatex on the X chromosome of a man.Thus it is a X linked recesive genetic defect in man.
Because of the sex linkage females are carrior of the disease and males are affected.
This is because when a gene containing a revessive haemophilia is present in a male it gets expressed since a male has only one X chromosome.
But in case of a female there is another X chromosome that can suppress the haemophilic gene. This is why females are not generally affected but become carriers of haemophilia.
hope it helps....
Because of the sex linkage females are carrior of the disease and males are affected.
This is because when a gene containing a revessive haemophilia is present in a male it gets expressed since a male has only one X chromosome.
But in case of a female there is another X chromosome that can suppress the haemophilic gene. This is why females are not generally affected but become carriers of haemophilia.
hope it helps....
Answered by
8
Answer:
Haemophilia is a sex-linked recessive disease. The defective genes present on the X chromosome only and not on the Y chromosome. As the father always contributes a Y chromosome and never passes an X chromosome to his son, the gene for haemophilia can never be passed from a father to his son.
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