Question

Explain why High-Ceiling (loop) Diuretics are the most efficacious oral diuretic agent available.

Answer 1

It is often called a high-ceiling diuretic because it is more effective than other diuretics. Furosemide decreases the sodium, chloride, and potassium reabsorption from the tubule. Subsequently, these ions are retained in the renal tubule and presented to the distal nephron.